Cross Linkers
Hetero-bifunctional
cross-linking reagents have activated esters and maleimide reactive groups.
These functional groups react with amines and sulfhydryl groups of proteins,
respectively. Enzyme-labeled haptens are prepared using hetero-bifunctional
cross-linking reagents such as EMCS or GMBS. The cross-linking reaction requires
neutral pH and mild temperature since it is necessary to maintain enzyme
activity and antibody titers in the cross-linking reaction. Hetero-bifunctional
cross-linking reagents with 3, 5, 7, or 10 linear carbon chains are available.
These linear aliphatic chains act as spacers between the two reactive sites and
their water-soluble reagents. They are more stable than the aromatic
cross-linking reagents such as succinimidyl-4-N-maleimidobenzoate in a
wider pH range.
Product Code: E018-10 Unit: 50 mg
Product Code: E018-12 Unit: 100 mg
Description:
Chemical Name: N-(6-Maleimidocaproyloxy)succinimideN-Succinimidyl-6-maleimidohexanoate Appearance: white or slightly yellow powder
Product Code: G005-10 Unit: 50 mg
Product Code: G005-12 Unit: 100 mg
Description:
Chemical Name: N-(4-Maleimidobutyryloxy)succinimideN-Succinimidyl-4-maleimidobutyrate Appearance: white powder
Product Code: H257-10 Unit: 50 mg
Description:
Chemical Name: N-(8-Maleimidocapryloxy)succinimide Appearance: colorless or pale yellow oil or waxy solid or powder
Product Code: K214-10 Unit: 50 mg
Description:
Chemical Name: N-(11-Maleimidoundecanoyloxy)succinimide Appearance: white or pale yellow oil or waxy solid
Product Code: S024-10 Unit: 50 mg
Description:
Chemical Name: N-(6-Maleimidocaproyloxy)sulfosuccinimide, sodium salt Appearance: white or slightly yellowish pink powder
Product Code: S025-10 Unit: 50 mg
Description:
Chemical Name: 103848-61-9 Appearance: white or slightly yellowish pink powder
Product Code: S026-10 Unit: 50 mg
Description:
Chemical Name: N-(8-Maleimidocapryloxy)sulfosuccinimide, sodium salt Appearance: white or slightly yellowish pink powder
Product Name: Sulfo-KMUS
Product Code: S250-10 Unit: 50 mg
Description:
Chemical Name: N-(11-Maleimidoundecanoyloxy)sulfosuccinimide, sodium salt Appearance: white or slightly yellowish pink powder
Product Name: SPDP
Product Code: S291-10 Unit: 100 mg
Description:
Chemical Name: Succinimidyl 3-(2-pyridyldithio)propionate Appearance: white or slightly yellow powder
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